PRP Platelet Rich Plasma Therapy Blood Injection Featured on ABC's Good Morning America

PRP is getting a lot of attention in the media lately...here is a link from Good Morning America. This treatment speaks to the concept that the body has a remarkable ability to heal itself. Through innovative technology, we are revolutionizing how we address treatment of tendon and cartilage injuries.

http://abcnews.go.com/Health/PainNews/Story?id=6895441&page=1

New Platelet Rich Plasma Studies Underway

As testament to the growth in the biologic sector, numerous orthobiologic companies worldwide are funding research & are obtaining grants with PRP use.



Applications of study include plantar fasciitis, achilles tendinosis, congestive heart failure, peripheral vascular disease, systemic sclerosis (scleroderma), knee MCL tears, perodontal tissue, aortic aneurysms, coronary artery bypass, tennis elbow, and rotator cuff tears among others. I am currently conducting research specifically on knee arthritis.
www.orthohealing.com

http://clinicaltrials.gov/ct2/results?term=platelet+rich+plasma

http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=1420

http://clinicaltrials.gov/ct2/show/NCT00198185?cond=%22Tendon+Injuries%22&rank=1

http://clinicaltrials.gov/ct2/show/NCT00761423

LA Times article emphasizes non surgical approach to arthritis

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Following the well publicized NEJM article suggesting the ineffective role of arthroscoopy in arthritis, many are looking for alternative treatments that are cost effective with little risk. This article from the LA Times highlights some options including an exercise program, physical therapy modalities, and weight loss. While I agree that physical therapy is beneficial, as is maintaining an active lifestyle; often we need to address the internal biochemical environment of the joint. This may be achieved with Platelet Rich Plasma Therapy. Our knee arthritis clinical trials continue to show promising results in most cases. I have the 3 mo data in & I am collecting 6 mo data in a few weeks from now. These results will be published.

http://www.latimes.com/features/health/la-he-knees22-2008sep22,0,42582.story

Dr Steven Sampson publishes new Platelet Rich Plasma article

My PRP review article is now published in the Current Reviews in Musculoskeletal Medicine. http://www.springerlink.com/content/5708408818n30275/ The online version is available, and the printed version is coming soon. The article includes nearly 50 literature sources and provides a comprehensive overview regarding platelet rich plasma usage in orthopaedics and sports medicine. Also, the review discusses the promising realm of orthobiologics and describes experiences with using platelet rich plasma for cartilage disorders and osteoarthritis.

I have been conducting research on arthritis with encouraging results so far. I am planning on collaborating with other leading physicians and publishing many more articles to advance the field of orthobiologics.

New FDA Approved Study with Adult Bone Marrow Stem Cells in Vascular Disease

Using One's own adult stem cells taken from bone marrow, researchers are studying the effects of potentially preventing amputation in ischemic (poor blood supply)limbs. Doctors do a minimally invasive procedure obtaining stem cells, then much like PRP or platelet rich plasma they increase the concentration and then inject it. Doctors are injecting multiple sights just beneath the tissue in the blood flow deprived extremity. We look forward to following this study & the results that follow.

http://www.biomet.com/patients/clinical_recruitment_padstudy.cfm

Adult Stem Cells for Arthritis?

Perhaps the next frontier beyond PRP is Stem Cells. While the topic is the subject of much controversy politically, technology now allows us to utilize adult stem cells opposed to embryonic cells to treat disease.

Stem Cells are the birthplace of platelets rich in healing properties, which can potentially program cells to regenerate tissue & cartilage. Currently stem cells can be retrieved via embryo (controversial in US), umbilical cord, bone marrow, peripheral blood, & in the near future adipose (fat) cells via liposuction.

Peripheral blood, or simply drawing blood from a patient's arm is the least invasive & most promising method. Patients require a shot or medication to release stem cells from the marrow to the blood stream. It can then be processed & used for injection. In the future patients may have the option to store unused stem cells for future use as well.

Stem cells are being used in the US mostly for cancer patients to assist in recovery from the ill effects of chemotherapy. A few practitioners are using them orthopaedically with reportedly good results in arthritis. Internationally there are centers where patients seek alternative treatment to serious diseases like spinal cord injury, multiple sclerosis, and ALS.


There is an adult stem cell organization which lists numerous articles & personal stories.

www.adultstemcelleducation.com

Multi Center Clinical trials of Platelet Rich Plasma Underway

Many trials are in the pipeline in efforts of obtaining FDA approval for PRP injections. There is a multi-center placebo controlled double blinded study underway looking at plantar fasciitis(heel pain) & lateral epicondylitis (tennis elbow).

http://www.biomet.com/patients/clinical_recruitment_recover.cfm

Also, Thanks to the many patients inquiring about info on docs around the country performing PRP procedures. Feel free to contact any of those listed in the link performing this particular study. At some point I may have a list of various PRP docs out there to help patients out. Please Continue to send requests.

On another note, we are currently examining the efficacy of Platelet Rich Plasma with osteoarthritis. We are collecting objective data on all patients injected.

Platelet Rich Plasma Cartilage/Arthritis Study in Rabbits

In a recent study from October 2007, a group from China was the first to document platelet rich plasma's ability to support chondrogenesis (cartilage cell growth). They took cartilage from the rabbit's ear, & mixed it with PRP and calcium chloride & thrombin (to form a matrix). Two months later, hard knobbles were found and seen on MRI, as well as histological analysis (cellular) and staining confirmed cartilage growth. Interestingly, there was no cartilage growth with the control group that received PRP alone. This study demonstrated successful formation of new cartilage with an injectable graft using PRP and cultured chondrocytes.

http://www.joms.org/article/PIIS0278239106021070/abstract